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Alternatives to Animal Testing – when science becomes cruelty-free 

Alternatives to Animal Testing - when science becomes cruelty-free 

It is estimated that over 115 million animals are used for scientific research and testing worldwide each year. This figure includes a wide range of animals, such as mice, rats, rabbits, primates and more. The actual number could be even higher since not all countries and institutions report their usage statistics comprehensively, which is alarming. Thankfully, the development of non-animal methods is growing, and fast. As a vegan business committed to cruelty-free practices, here in Not to Die For* It’s essential to highlight and support alternatives to animal testing. 

Computer modeling 

Computer modeling, also known as in silico methods, uses advanced algorithms and simulations to predict the biological effects of substances without the need for animal testing. By analyzing chemical properties and biological data, computer models can forecast how substances will behave in the human body, assessing toxicity, efficacy, and safety. This approach not only reduces the reliance on animal models but also allows for the rapid and cost-effective screening of large numbers of compounds, providing more accurate and relevant results for human health.

Bioprinting

Bioprinting is a cutting-edge technology that uses 3D printing techniques to create living tissues and organ structures from human cells. By precisely layering bio-inks—substances composed of living cells and supportive materials—bioprinting can replicate the complex architecture of human tissues such as skin, liver, and heart. Bioprinting creates tissues that accurately test the safety and efficacy of drugs, cosmetics, and other products, providing more human-relevant data.

This innovative method not only reduces the need for animal testing but also holds the potential to revolutionize medical research and personalized medicine.

Bioprinting: an alternative to animal testing

Human Tissue Models 

This model involves the use of human cells and tissues to create more accurate and relevant testing systems for studying biological responses. Researchers derive these models from donated tissues or engineer them in the lab, replicating the structure and function of human organs. Examples include liver slices, skin equivalents, and complex organ-on-a-chip systems. By mimicking human physiology, human tissue models provide precise data on toxicity, drug efficacy, and disease mechanisms, offering a superior alternative to animal testing. This approach not only enhances the reliability of research findings but also adheres to ethical standards by eliminating the need for animal use.

Human Volunteer models

Remember COVID-19, when big pharmacies tested their vaccines on humans before launching them worldwide? Well, human volunteer studies involve conducting research directly on human participants to gather data on health outcomes, drug effects, and disease processes. These studies can take the form of clinical trials, where new treatments or drugs are tested for safety and efficacy, or observational studies, which track health metrics in specific populations over time. Conducted under strict ethical guidelines and regulatory oversight, human volunteer studies provide the most relevant and reliable data for human health, offering a critical alternative to animal testing. This approach ensures that findings are directly applicable to humans, enhancing the development of safe and effective medical treatments.

We recently shared tips on finding cruelty-free alternatives to products that use animal testing. If you want to avoid the hassle of reading labels, you can check our shop for curated vegan and cruelty free options.

At Not to Die For, we actively find and support new non-animal alternatives to testing.As a cruelty-free and vegan business, we believe in ethical practices that protect both animals and our planet. 

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